IMAX Discovery’s Technology Platforms
IMAX Discovery is dedicated to the identification of innovative flavors, fragrances and taste imparting or modulating ingredients, discovered and isolated from nature as well as from chemical synthesis, for the food and beverage, pet food, cosmetic and perfume industry.
IMAX Discovery has established and validated exclusive technology platforms allowing to investigate human taste and olfactory receptors based on cellular assays in order to screen large numbers of compounds for flavors, fragrances and taste imparting or modulating molecules. This represents a paradigm shift in quality and productivity as opposed to testing in human sensory panels.
For this identification purpose, IMAX Discovery provides access to a proprietary natural compound collection of > 100,000 individual test samples comprising the world largest pure natural product compound collection (NatPure) as well as extracts and pre-purified fractions and to a synthetic compound collection consisting of 240,000 compounds characterized by a high level of novelty and diversity.
Humans monitor the chemical composition of the environment and food with three different sensory pathways: the olfactory system, the taste system and the somatosensory system.
Taste is the sense that guides and helps organisms to identify and consume essential nutrients while avoiding toxins and indigestible materials. For humans, this means recognizing and distinguishing the five basic taste modalities sweet, bitter, salty, sour and umami.
The molecular sensors for the different taste modalities are membrane proteins belonging to either the family of G protein coupled receptors (bitter, sweet and umami) or the family of ion channels (salty and sour).
Apart from the sensation of the classic taste modalities, we also experience effects like cooling, spicy, astringency etc. These somatosensory effects are mediated by receptors located on trigeminal nerve fibers throughout the oral cavity; most of these receptors are members of the family of transient receptor potential (TRP) channels.